Individuals with damage to the Dorsolateral Prefrontal Cortex (DLPFC) have problems with such things as planning, shifting attention, response perseveration and decision-making. Finnish researcher Laakso and his team also found that alcoholics with antisocial personalities had reduced gray matter volume in the left DLPFC and the right OFC when compared with controls. Here
fMRI studies from 2000, 2002, 2004 and 2005 have also shown abnormal functioning in that same area (DLPFC) in individuals with APD, Borderline and Psychopathy (Cluster B)
Schneider (2000) Here Dolan ( 2002) Here Völlm (2004) Here and Pridmore (2005) Here
A more recent study of interest (October, 2009) asks; Do psychopathic patients use their DLPFC when making decisions in moral dilemmas? Here Makes for some very interesting reading.
Here some other research of interst on the subject;
Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making. (Sept. 2009) Here
Brain Abnormalities in Antisocial Individuals: Implications for the Law (Yang et al., 2008) Here